Effects of cannabidiol and tetrahydrocannabinol on the microbiome, endocannabinoids and neuroinflammation in HIV
PI: Ron Ellis, MD, PhD
This study will examine the microbiome and endocannabinoid system in people with HIV and how they relate to neuroinflamation and the blood-brain-barrier.
Efficacy of inhaled cannabis versus placebo for the acute treatment of migraine
PI: Nathaniel Schuster, MD
This is a clinical study to determine the effect of THC and CBD on acute migraine.
The Effects of THC on Glucose Metabolism and Endothelial Function in Subjects with Type 2 Diabetes
PI: Jeremy Pettus, MD
This study will seek to determine the effects of THC use on glucose metabolism
The role of cannabidiol in anandamide-related improvement in alexithymia and health outcomes
PI: Erin Morgan, PhD
This study will examine whether CBD will reduce alexithymia and inflammation in people with HIV
Cannabis, inflammation, and the brain in persons with HIV
PI: Jennifer Iudicello, PhD
This study will examine the effects of chronic cannabis use and the role of the endocannabinoid system on persistent inflammation in people with HIV.
Effects of CBD on blood pressure and substrate metabolism during metabolic syndrome
PI: Rudy Ortiz, PhD
This is a pre-clinical study regarding the effects of CBD on blood pressure and factors related to metabolic syndrome
The Effects of Cannabidiol (CBD) on Symptoms of Severe Autism
PI: Doris Trauner, MD
This clinical trial is examining if and how cannabidiol (CBD), a chemical found in the cannabis plant, provides therapeutic benefit to children with severe autism spectrum disorder (ASD). The trial is funded by a grant from the Ray and Tye Noorda Foundation in partnership with and based on recommendations from the Wholistic Research and Education Foundation.
Cannabidiol for Sedative/Hypnotic-sparing Management of Insomnia in Adults
PI: Mariana Cherner, PhD
It is estimated that up to a third US adults suffer from sleep problems, which are in turn associated with sub-optimal, and sometimes compromised, daily functioning. Sedative and hypnotic medications constitute the main pharmacologic treatment for insomnia, but they are habit-forming and associated with adverse next-day “hangover” effects, including impaired driving and risk of falls.
The Role of Cannabidiol (CBD) in Regulating Meal Time Anxiety in Anorexia Nervosa
PI: Guido Frank, MD
Because there are no proven treatments that normalize core symptoms in adult anorexia nervosa (AN), a disorder with high chronicity and mortality, many individuals seek out alternative approaches to care. Recent evidence has suggested that exaggerated anxiety and diminished reward or motivation to eat play a key role in causing AN symptoms and poor outcome.
Cannabis Use and the Endocannabinoid System in Bipolar Disorder
PI: William Perry, Ph.D. & Jared Young, Ph.D
This study will look at the impact of chronic cannabis use as well as the effects of acute administration of the principal constituents of cannabis on cognition and brain levels of endogenous cannabinoids and the neurotransmitter dopamine.