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CNN Chief Medical Correspondent Dr. Sanjay Gupta interviewed Dr. Doris Trauner, lead researcher of CMCR's study on childhood autism. The clinical trial is examining how CBD can affect the brains of children with autism. Read the story with video clips from the interview here.

 

 

 

 

 

 

 

 

 

 

 

Medicinal Cannabis and Cannabinoid-Based Medicine:
Progress, Policy, and Partnership

 

PDF of the 2022 CMCR Symposium Program

Day 1: Thursday, April 21, 2022

8:00-8:05 Welcome from the CMCR Director, Igor Grant, MD - LINK to VIDEO

2022 CMCR Symposium Awards

8:05-8:40 Daniele Piomelli, PhD, MD (h.c.) - 2022 CMCR Pioneer in Medicinal Cannabis Research Award

Presentation of Award and Keynote Address - Trekking on the Endocannabinoid Trail - LINK to VIDEO

This award honors leaders in cannabis and cannabinoid research conducting basic and translational research of cannabinoids, other constituents of cannabis, and the endocannabinoid system. The recipient’s work has led to significant advancements in our understanding of the mechanism and physiological effects of cannabinoids and related compounds.

8:40-9:15 Donald Abrams, MD - 2022 CMCR Award for Advancing Cannabis and Cannabinoids as Therapeutics

Presentation of Award and Keynote Address - Conducting Clinical Cannabis Research Tribulations and Trials - LINK to VIDEO 

This award honors those whose work has led to significant changes in our knowledge of or an expansion to the therapeutic use of cannabis and cannabinoid-based medicines. Recipients come from a diverse array of backgrounds, including drug development, medicine, public policy, and advocacy.

9:15-9:20 5-minute break

9:20-9:55 Moderated panel discussion and Q&A with 2022 CMCR Symposium Award Recipients & previous award recipients - LINK to VIDEO

2022 Award Recipients: Daniele Piomelli, PhD and Donald Abrams, MD

2019 Award Recipients: Raphael Mechoulam, PhD and Geoffrey Guy, MD

9:55-10:00 5-minute break

CMCR Special Lecture

10:00-10:20 Raphael Mechoulam, PhD - Endogenous Anandamide-like Compounds - LINK to VIDEO

10:20-10:30 Q&A moderated by Igor Grant, MD

Panel 1: Update on Federal activities affecting cannabis research - LINK to VIDEO

10:30-11:55 Panel discussion and Q&A moderated by Steve Gust, PhD, Advisor to CMCR

The invited Federal stakeholders will discuss future directions in regulatory policy related to medicinal cannabis, funding for medicinal cannabis research, and access to cannabis and cannabinoids for research purposes.

Panelists:

Trelaine Ito, Deputy Appropriations Director and Legislative Assistant to Senator Schatz - "Congressional Actions Related to Cannabis Affecting Research" 

David Shurtleff, PhD, National Center on Complementary and Integrative Health (NCCIH), NIH - "Cannabinoid Research at NIH" 

Cassandra Taylor, PhD, Center for Drug Evaluation and Research, FDA - "FDA Role in Regulation of Cannabis" 

Richard (Rik) Kline, PhD, Chief, Chemistry and Pharmaceutics Branch, NIDA - "Role of the NIDA Drug Supply Program in Providing Cannabis Products for Research" 

11:55-12:00 5-minute break

12:00-1:00 Poster Session - LINK to pre-recorded VIDEOS

 


Day 2: Friday, April 22, 2022

State of the Science Lecture Series

Welcome - LINK to VIDEO

Neuroprotective Effects of Cannabis and Cannabinoids: Evidence from PTSD - LINK to VIDEO

8:00-8:15 Leah Mayo, PhD - Protective Effects of Elevated Anandamide During Stress Exposure

8:15-8:30 Christine Rabinak, PhD - Cannabinoid Modulation of Corticolimbic Activation to Threat 

8:30-8:45 Marcel Bonn-Miller, PhD - Cannabis and PTSD

8:45-8:55 Q&A moderated by Arpi Minassian, PhD

8:55-9:00 5-minute break

Cannabinoids and COVID-19 - LINK to VIDEO

9:00-9:15 Michelle Sexton, ND - Cannabis and COVID-19 Infection

9:15-9:30 José Alexandre S. Crippa, MD, PhD - Cannabidiol (CBD) and COVID-19 

9:30-9:40 Q&A moderated by Ajay Bharti, MD

FAAH inhibitor in the Treatment of Substance Use Disorders - LINK to VIDEO

9:40-9:55 Deepak D'Souza, MD - Blunting Cannabis Use Disorder by Targeting the Endocannabinoid System 

9:55-10:00 Q&A moderated by Giordano de Guglielmo, PharmD, PhD

10:00-10:05 5-minute break

Panel 2: Promoting industry and university partnership to enhance cannabis research - LINK to VIDEO

10:05-10:55 Panel discussion and Q&A moderated by Igor Grant, MD

Panelists will be invited to discuss partnerships between universities and the cannabis industry, providing models and exploring synergies.

Panelists: Mahmoud ElSohly PhD, Josh Hoerner PhD, Mark Ware MBBS, MRCP, MSc ICD.D

10:55-11:00 5-minute break

Panel 3: Early experience of federally-licensed cannabis growers - LINK to VIDEO

11:00-11:45 Panel discussion and Q&A moderated by Tom Marcotte, PhD

Representatives from DEA-licensed cannabis growers will discuss their early experience and future goals to produce cannabis and cannabinoid-based products for research.

Panelists: Justin Abril (Royal Emerald Pharmaceuticals), Steve Groff MD (Groff North America), George Hodgin MBA (Biopharmaceutical Research Company), Sue Sisley MD (Scottsdale Research Institute)

11:45-12:00 Closing Remarks from the CMCR Director, Igor Grant, MD - LINK to VIDEO

 

LINK to 2022 CMCR Symposium Sponsors

LINK to CMCR Symposia Series

 

 

 

 

Exploring the Entourage:
The Therapeutic Potential of Minor Cannabinoids, Terpenes, and Flavonoids

 

The Center for Medicinal Cannabis Research (CMCR) hosted a virtual, two-day symposium on October 12-13, 2023 highlighting the state of science in medicinal cannabis research. Whereas the majority of current research focuses on delta-9-THC and cannabidiol, the 2023 CMCR Symposium highlighted emerging clinical and translational research on the "other" constituents of cannabis (minor cannabinoids, terpenes, and flavonoids) and the entourage effect.

 

Day 1: Thursday, October 12, 2023

8:00-8:05 Welcome from the CMCR Director, Igor Grant, MD

2023 CMCR Symposium Awards

8:05-8:40 Marilyn Huestis, AB, MS, PhD - 2023 CMCR Pioneer in Medicinal Cannabis Research Award

Keynote Address - Thirty years of Human Cannabinoid Administration Studies Contributing to the Development of Medical Cannabinoids - LINK to VIDEO

This award honors leaders in cannabis and cannabinoid research conducting basic and translational research of cannabinoids, other constituents of cannabis, and the endocannabinoid system. The recipient’s work has led to significant advancements in our understanding of the mechanism and physiological effects of cannabinoids and related compounds.

8:40-9:15 Margaret Haney, PhD - 2023 CMCR Award for Advancing Cannabis and Cannabinoids as Therapeutics

Keynote Address - Cannabis Misuse and Therapeutic Potential: Placebo-controlled Laboratory Studies - LINK to VIDEO

This award honors those whose work has led to significant changes in our knowledge of or an expansion to the therapeutic use of cannabis and cannabinoid-based medicines. Recipients come from a diverse array of backgrounds, including drug development, medicine, public policy, and advocacy.

9:15-9:20 5-minute break

9:20-9:55 Moderated panel discussion and Q&A with 2023 CMCR Symposium Award Recipients - LINK to VIDEO

Videos of congratulations from 2022 Award Recipients - LINK to VIDEO from Dr. Daniele Piomelli & LINK to VIDEO from Dr. Donald Abrams

9:55-10:00 5-minute break

CMCR Special Lectures

10:00-10:20 Doris Trauner, MD - A Randomized Clinical Trial of Cannabidiol for Behavioral Problems in Boys with Severe Autism - LINK to VIDEO

10:20-10:30 Q&A moderated by JH Atkinson, MD

10:30-10:50 Marcel Bonn-Miller, PhD - A Double-Blind Randomized, Placebo-Controlled Study of the Safety and Effects of CBN With and Without CBD on Sleep Quality - LINK to VIDEO

10:50-10:55 Q&A discussion moderated by JH Atkinson, MD

10:55-11:00 5-minute break

Panel 1: Update on Federal activities affecting cannabis research

11:00-11:55 Panel discussion and Q&A moderated by Steve Gust, PhD, Advisor to CMCR

Panelists:

David Shurtleff, PhD, Deputy Director, National Center for Complementary and Integrative Health

Cassandra Taylor, PhD, Botanical Products, Center for Drug Evaluation and Research, US Food and Drug Administration

Richard (Rik) Kline, PhD, Chief, Chemistry and Pharmaceutics Branch, NIDA

11:55-12:00 Introduction to the poster session

12:00-1:00 Poster Session - LINK to VIDEOS

 


Day 2: Friday, October 13, 2023

State of the Science Lecture Series

The Entourage: Minor Cannabinoids, Terpenes, and Flavonoids

8:00-8:05 Welcome

8:05-8:20 Ziva Cooper, PhD - Assessing the Analgesic and Subjective Effects of Inhaled Beta-Caryophyllene Alone and with Delta-9 THC in healthy volunteers - LINK to VIDEO

8:20-8:35 Ryan Vandrey, PhD - Behavioral Pharmacology of D-Limonene and THC - LINK to VIDEO

8:35-8:50 Sara Jane Ward, PhD - Anti-allodynic effects of Beta-caryophyllene in rodent models of neuropathic pain - LINK to VIDEO

8:55-9:00 5-minute break

9:00-9:15 Jonathan C. Arnold, PhD - Anti-seizure and Entourage Effects of Plant Cannabinoids in Preclinical Models - LINK to VIDEO

9:15-9:30 John Streicher, PhD - Terpenes from Cannabis Sativa are Cannabimimetic and Selectively Enhance Cannabinoid Activity - LINK to VIDEO

9:30-10:00 Q&A moderated by Ziva Cooper, PhD and Patrick Still, PhD

10:00-10:05 5-minute break

Panel 2: Use of minor cannabinoids, terpenes, and flavonoids in the community

10:05-10:55 Panel discussion and Q&A moderated by Igor Grant, MD

Panelists:

Sherry Yafai, MD, Providence St. John's Medical Center

Bonni Goldstein, MD, Medical Director, CannaCenters

Michelle Sexton, ND, UC San Diego

Dale Gieringer, PhD, California NORML

10:55-11:00 5-minute break

11:00-11:20 Linda Hill, MD, MPH - The State of Cannabis: A Survey of 5,000 Californians - LINK to VIDEO

11:20-11:25 Q&A discussion moderated by David Grelotti, MD

11:25-11:45 Tom Marcotte, PhD - Evaluation of Field Sobriety Tests for Identifying Drivers Under the Influence of Cannabis - LINK to VIDEO

11:45-11:50 Q&A discussion moderated by David Grelotti, MD

11:50-12:00 Closing Remarks from the CMCR Director, Igor Grant, MD

 

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