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Exploring the Entourage: The Therapeutic Potential of Minor Cannabinoids, Terpenes, and Flavonoids

The Center for Medicinal Cannabis Research (CMCR) hosted a virtual, two-day symposium on October 12-13, 2023 highlighting the state of science in medicinal cannabis research. Whereas the majority of current research focuses on delta-9-THC and cannabidiol, the 2023 CMCR Symposium highlighted the emerging clinical and translational research on the "other" constituents of cannabis (minor cannabinoids, terpenes, and flavonoids) and the entourage effect. The symposium kicked off with keynote addresses from the 2023 CMCR award recipients followed by a series of scientific talks covering clinical and translational aspects of medicinal cannabis research alongside panel discussions of changes to the federal landscape related to cannabis research, use of minor cannabinoids, terpenes, and flavonoids in the community, and accessing novel constituents of cannabis for clinical research.

Virtual Event
October 12-13, 2023
8:00AM-12:00PM PDT

 

Registration

Registration is now closed.

 

Agenda at a Glance

Day 1: Thursday, October 12, 2023
Welcome from the CMCR Director, Igor Grant, MD
2023 CMCR Symposium Awards (8:00 - 10:00 AM)
CMCR Special Lecture (10:00 - 10:30 AM)
Panel 1: Update on Federal activities affecting cannabis research (10:30 AM - 12:00 PM)
Poster Session (12:00 - 1:00 PM); View the pre-recorded videos in the Poster Session here.

Day 2: Friday, October 13, 2023
State of the Science Lecture Series - The Entourage: Minor cannabinoids, Terpenes and Flavonoids (8:00 - 10:05 AM)
Panel 2: Use of minor cannabinoids, terpenes, and flavonoids in the community (10:05 - 10:55 AM)
Panel 3: Lectures from Linda Hill, MD, MPH and Tom Marcotte, PhD (11:00 - 11:45 AM)
Closing Remarks from the CMCR Director, Igor Grant, MD (11:45 AM - 12:00 PM)

View the detailed agenda and video recordings here.

 

Speakers

Igor Grant, MD, FRCP(C) Distinguished Professor of Psychiatry, Director of the Center for Medicinal Cannabis Research, UC San Diego
David J. Grelotti, MD Associate Clinical Professor of Psychiatry, Medical Director, Center for Medicinal Cannabis Research, UC San Diego
Tom Marcotte, PhD Professor of Psychiatry, Co-Director, Center for Medicinal Cannabis Research, UC San Diego
JH Atkinson, MD, Professor of Psychiatry (Emeritus), Co-Director, Center for Medicinal Cannabis Research, UC San Diego
Marilyn Huestis, AB, MS, PhD Professor & Senior Fellow, Institute of Emerging Health Professions, Thomas Jefferson University & Science and Policy Advisor, Pinney Associates & President, Huestis and Smith Toxicology LLC
Margaret Haney, PhD Professor of Neurobiology, Columbia University Irving Medical Center, New York State Psychiatric Research Center
Doris Trauner, MD Professor of  Neurosciences, UC San Diego
Marcel Bonn-Miller, PhD Chief Scientific Officer, Charlotte's Web
Steve Gust, PhD, Advisor to the Center for Medicinal Cannabis Research
David Shurtleff, PhD Deputy Director, National Center for Complementary and Integrative Health (NCCIH), NIH
Cassie Taylor, PhD Botanical Products, Center for Drug Evaluation and Research, US Food and Drug Administration
 Richard (Rik) Kline, PhD Chief, Chemistry and Pharmaceutics Branch, NIDA
Ziva Cooper, PhD Associate Professor of Psychiatry & Biobehavioral Sciences, Director of the UCLA Center for Cannabis and Cannabinoids, UCLA
Patrick Still, PhD Program Director, Basic and Mechanistic Research Branch, NCCIH, NIH
 Ryan Vandrey, PhD Professor, Behavioral Pharmacology Research Unit, Johns Hopkins University School of Medicine
Sara Jane Ward, PhD Assistant Professor of Neural Sciences, Center for Substance Abuse Research, Temple University
Jonathan C. Arnold, PhD Professor of Cannabinoid Pharmacology, Deputy Academic Director, The Lambert Initiative for Cannabinoid Therapeutics, University of Sydney
John Streicher, PhD Professor of Pharmacology, University of Arizona
Sherry Yafai, MD Providence St. John's Medical Center
 Bonni Goldstein, MD Medical Director, CannaCenters
 Michelle Sexton, ND UC San Diego
Dale Gieringer, PhD California NORML
Linda Hill, MD, MPH Distinguished Professor and Assistant Dean, School of Public Health, UC San Diego

View more details about the 2023 Speakers here.

 

Supporters

The CMCR wishes to acknowledge the following for the support of our work:

State of California

National Institutes of Health

Noorda/Wholistic Research and Education Foundation

University of California / UC San Diego

Jazz Pharmaceuticals

And our individual supporters



Posters

The poster session took place on Thursday, October 12, 2023 from 12:00PM-1:00PM Pacific Time. 

Each person selected to present a poster was assigned a breakout room linked to the symposium conference portal. In the breakout room, presenters engaged in a discussion with other conference-goers “live” about their research. Presenters prepared brief Powerpoint-style presentations to facilitate discussion.

View the pre-recorded videos in the Poster Session here.

 

Contact

Please direct questions to This email address is being protected from spambots. You need JavaScript enabled to view it..

 

 

Raphael Mechoulam, towering figure in cannabis research has passed

CMCR mourns the passing on March 9, 2023 of Professor Raphael Mechoulam, commonly regarded as the father of cannabis research. He is recognized for his ground breaking studies on the structure and function of THC, as well as characterizing cannabidiol and other cannabinoids. In 1992, his laboratory discovered anandamide, the body’s first characterized signaling molecule within the endocannabinoid system. Though a towering figure, Professor Mechoulam was always generous with his advice and support and was crucial in guiding the efforts of CMCR in our early years. He continued his connection with CMCR over the decades and in 2019 we were pleased to honor him with CMCR’s Pioneer in Medicinal Cannabis Research Award. He is pictured here receiving that award. More information on Professor Mechoulam’s career can be found in this link from the International Cannabinoid Research Society which he helped to found.

California State Senate - Dr. Igor Grant - March 2023

On March 13, 2023, Dr. Igor Grant presented to the California State Senate Committee on Business, Professions, and Economic Development. The topic of the oversight hearing was "The State of Cannabis Regulation in California: Progress, Challenges, and Next Steps" with panels of representatives from various agencies reporting on the status of cannabis tax funds from California Proposition 64. The full hearing can be found at this LINK and Dr. Grant's presentation begins at 4:36:30.

Experts reflect on what new law might mean for cannabis research

Nick Zagorski, Psych News, March 9, 2023. Drs. Igor Grant and Ziva Cooper comment on how the Medical Marijuana and Cannabidiol Research Expansion Act law will impact medical cannabis research. Read the article here.

CME credits for 2022 CMCR Symposium - closed

The Center for Medicinal Cannabis Research is pleased to offer continuing medical education (CME) credits for select 2022 CMCR Symposium presentations. These modules were open for credit until February 2024 and are now closed.

Learners will need to create an account HERE to claim credits. If you are a UC San Diego or UC San Diego Health employee, please log in with your @ucsd.edu SSO credentials (do not use your health email account).  

Once your account is created, you may browse CMCR Symposium accredited content HERE.

When you have completed the education click on POST-TEST to attest to having viewed all or some of the education and claim credit. Then click on SHOW RESULTS.

Click on MyCME or EVALUATION & CERTIFICATES to access and download certificates.

 

Accreditation

The University of California San Diego School of Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

The University of California San Diego School of Medicine designates this Enduring Material activity for a maximum of 4.00 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

AAPA: AAPA accepts certificates of participation for educational activities certified for AMA PRA Category 1 Credit™ from organizations accredited by ACCME or a recognized state medical society. Physician assistants may receive a maximum of 4.00 hours of Category 1 credit for completing this program.

Nurses: For the purpose of recertification, the American Nurses Credentialing Center accepts AMA PRA Category 1 Credits™ issued by organizations accredited by the ACCME. For the purpose of relicensure, the California Board of Registered Nursing accepts AMA PRA Category 1 Credits™ (report up to 4.00 hours of credit and list "CME Category 1" as the provider number).

Pharmacists: The California Board of Pharmacy accepts as continuing education for pharmacists coursework which meets the standard of relevance to pharmacy practice and is accepted as continuing education by the Medical Board of California.

Psychologists: The California Board of Psychology recognizes and accepts AMA PRA Category 1 Credit(s)™ for license renewal. Psychologists outside of California should check with their state and local boards to ensure that ACCME accredited activities are acceptable for renewal.

 

 

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