Go to CURRENT / COMPLETED Studies

Current Studies

PI: Ziva Cooper, PhD

This clinical trial will examine the effects of combining THC and cannabigerol on pain and other outcomes.

PI: Daniele Piomelli, PhD

This is a preclinical study to investigate antinociceptive effects of THC, CBD, and a combination of THC and CBD on sickle cell disease.

PI: Jennifer Thomas, PhD

This study will explore how prenatal exposure to CBD and other cannabinoids affects fetal development.

PI: Jennifer Iudicello, PhD

This project will combine a clinical observational study with two preclinical models to investigate whether cannabis can protect people with HIV from blood-brain-barrier damage by reducing inflammation and promoting mitochondrial homeostasis.

PI: Scott Letendre, MD

This is a clinical study looking at the intersection of cannabis, HIV, and the Central Nervous System.

PI: Jennifer Iudicello, PhD

This study will examine the effects of chronic cannabis use and the role of the endocannabinoid system on persistent inflammation in people with HIV.

PI: Jamie Inman, PhD

This is a preclinical study to investigate genetic susceptibility to adverse and/or beneficial effects on anxiety of acute cannabinoid exposure.

PI: Kristin Cadenhead, MD

This clinical trial will explore the effectiveness of cannabidiol (CBD), in reducing symptoms and improving cognition in early psychosis. Additionally, this trial will examine the effect of CBD on the biological response to stress, and the effect of CBD on eating behavior induced by antipsychotic medication.

PI: Ron Ellis, MD, PhD

This study will examine the microbiome and endocannabinoid system in people with HIV and how they relate to neuroinflamation and the blood-brain-barrier.

PI: Charles Taylor, PhD

This is a clinical study to determine the effect of CBD on anxiety disorders.

PI: Edythe London, PhD

This is a clinical study to evaluate the efficacy of cannabidiol in reducing cigarette smoking.

PI: Nicholas Bernthal, MD

This study will explore CBD as a perioperative analgesic for orthopaedic pain.

PI: Nicholas DiPatrizio, PhD

This study will examine the impact of cannabis exposure on gut barrier function in metabolic disease and experimental colitis

PI: Catherine Cahill, PhD

This study will investigate whether terpenes have analgesic potential and whether they enhance endocannabinoid concentrations in the brain

PI: Zhi-Ling Guo, MD, PhD

This study aims to determine the influence of sex differences on CBD’s effects on cardiovascular functions.

PI: Catherine Cahill, PhD

This is a preclinical study to investigate whether terpenes can modulate both sensory and affective dimensions of ongoing chronic pain. 

PI: Fadel Zeidan, PhD

This is a clinical study to determine if vaporized cannabis directly reduces evoked chronic low back pain.

PI: Jeremy Pettus, MD

This study will seek to determine the effects of THC use on glucose metabolism

PI: Erin Morgan, PhD

This study will examine whether CBD will reduce alexithymia and inflammation in people with HIV

PI: Veena Ranganath, MD

The overall goal of this proof-of-principle proposal is to examine the efficacy and safety of CBD treatment as adjunctive to the medical management of Rheumatoid Arthritis (RA) patients with moderate to severe disease activity.

PI: Arpi Minassian, PhD

This study will utilize a cross-species approach to delineate the effects EC system activation has on HIV-relevant cognitive and motivational domains.