CMCR 2019 Symposium

The Center for Medicinal Cannabis Research (CMCR) hosted a one-day symposium on October 18, 2019 celebrating the pioneers and exploring the progress, promise, and challenges of medicinal cannabis research.
During the symposium, two pioneers in medicinal cannabinoid research were honored:
Raphael Mechoulam, PhD (Hebrew University) - Dr. Mechoulam has made groundbreaking discoveries in the field of cannabinoid chemistry since the 1960s. He coined the term “cannabinoid”. In 1964, Dr. Mechoulam’s laboratory first identified and synthesized delta-9-tetrahydrocannabinol (“THC”), the main psychoactive component of cannabis. Since then, his team has gone on to identify the structure of most of the cannabinoids and their metabolites and to discover the endogenous cannabinoids anandamide and 2-arachidonylglycerol (2-AG). An author of more than 300 publications, Dr. Mechoulam holds over 20 patents. Known for his scientific vision and warmth, we are pleased to honor his achievements and outstanding contribution to the field of medicinal cannabis with the Pioneer in Medicinal Cannabis Award.
Geoffrey Guy, MBBS (GW Pharmaceuticals) - Dr. Guy founded GW Pharmaceuticals and has served as its Chairman since 1998. Dr. Guy created Epidiolex, the first formulation of cannabidiol to receive approval from the US Food and Drug Administration, and Sativex. He continues to lead innovation and new product discovery for cannabinoid-based medicine. He has been the physician in charge of over 300 clinical studies including pharmacokinetic, pharmacodynamic, and dose-ranging studies, controlled clinical trials, and large scale multi-centered studies and clinical surveys. An innovator in medical research and global drug development for his entire career, the CMCR is pleased to honor his achievements and outstanding contribution to the field of medicinal cannabis with the CMCR Award for Advancing Cannabis and Cannabinoids as Therapeutics.
| Introduction/Overview | Igor Grant, MD, CMCR Director, UC San Diego | |||
| Pioneer in Medicinal Cannabis Research Award | Raphael Mechoulam, PhD, Hebrew University of Jerusalem | |||
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Advancing Cannabis and Cannabinoids as Therapeutics Award
Presentation on Cannabinoid Therapeutics: Harnessing the medicinal properties of cannabis: from plant to medicine |
Geoffrey Guy, MBBS, GW Pharmaceuticals
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Discussion/Future Directions |
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The Anti-Inflammatory Properties of Cannabinoids |
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Transdermal cannabidiol in animal model of arthritis | Karin Westlund-High, PhD, University of New Mexico | ||
| The immunomodulary effect of cannabis use in HIV | Jennifer Manuzak, PhD, University of Miami Miller School of Medicine | |||
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| Cannabidiol and receptor physiology | Fabricio Moreira, PhD, Universidade Federal de Minas Gerais, Brazil | |||
| Cannabidiol ameliorates the memory-impairing effects of THC in non-human primates | Michael Taffe, PhD, UC San Diego | |||
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Cannabidiol in reducing nicotine dependence | Olivier George, PhD, UC San Diego | ||
| Discussion/Future Directions | ||||
The Potential Opioid Sparing Effects of Cannabinoids |
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| The endocannabinoid system and pain | Aron Lichtman, PhD, Virginia Commonwealth University | |||
| Human lab experiments of cannabinoids and pain | Ziva Cooper, PhD, UCLA | |||
| Does cannabis moderate opioid use in chronic pain? | Michelle Sexton, ND, UC San Diego | |||
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Safeguarding, Educating, and Learning from Cannabis use in the Public Sphere |
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| Recent findings on the effects of medicinal and recreational cannabis laws on youth consumption | Denise Walker, PhD, University of Washington | |||
| Impact and detection of cannabis impaired driving | Thomas Marcotte, PhD, UC San Diego | |||
| What are the promises and limitations of various cannabinoid testing platforms | Robert Fitzgerald, PhD, UC San Diego | |||
| Discussion/Future Directions | ||||
| State of California Approach | Discussants | |||
| Panel Discussion |
Lori Ajax, Chief, California Bureau of Cannabis Control | |||
| Tom Lackey, California Assemblyman District 36 | ||||
Achieving Priorities in Medicinal Cannabis Research |
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| Introduction | Igor Grant, MD, CMCR Director, UC San Diego | |||
| Public-private partnerships to advance cannabis and cannabinoid based medicines | Gail Taylor, BSc, PhD, FSB, UC Davis and University of Southampton | |||
Legislative and Regulatory Issues |
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| Update from HHS: Supply and Regulatory Issues | Steve Gust, PhD, NIDA | |||
| Legislative initiatives to facilitate medicinal cannabinoid research | Trelaine Ito, MS, Office of US Senator Brian Schatz | |||
| Perspectives and opportunities from industry and philanthropy | Discussants | |||
| Panel Discussion |
Alice Mead, JD, Greenwich Biosciences |
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| Pelin Thorogood, MBA, Wholistic Research and Education Foundation | ||||
| George Hodgin, Biopharmaceutical Research Company | ||||
| Hunter Land, MS, Canopy Growth | ||||
| Dennis Kim, MD, MBA, Emerald Bioscience | ||||
| Closing Remarks | Igor Grant, MD, CMCR Director, UC San Diego | |||
CMCR 2018 Symposium - Cannabis and Health: Opportunities and Challenges in the New Era
The Center for Medicinal Cannabis Research (CMCR) hosted a one-day symposium exploring emerging issues related to basic and clinical cannabinoid science, public health and safety implications, and regulatory challenges in conducting cannabis research.
Hilton San Diego Bayfront
San Diego, California
Friday, June 8, 2018
CMCR 2018 Symposium
The Center for Medicinal Cannabis Research (CMCR) hosted our inaugural symposium series on June 8, 2018 exploring emerging issues related to basic and clinical cannabinoid science, public health and safety implications, and regulatory challenges in conducting cannabis research.
| Topic | Speaker | |
| 7:30am | Continental Breakfast | |
| 8:00am | Introduction/Overview | Igor Grant, MD UC San Diego |
| The health impact of cannabis | Daniele Piomelli, MD, PhD, PharmD UC Irvine |
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| 9:00am | Examples of emerging therapeutic potentials of medicinal cannabis | |
| Moderator | Mark Wallace, MD UC San Diego |
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| Therapeutic potential of cannabis for pain alone and as an adjunct to opioids | Ziva Cooper, PhD Columbia University New York State Psychiatric Institute |
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| Cannabis & PTSD: A long and winding road absent good scientific data | Marcel Bonn-Miller, PhD University of Pennsylvania |
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| Potential utility of cannabidiol in the treatment of behavior problems in children with autism | Doris Trauner, MD UC San Diego Rady Children’s Hospital |
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| Medicinal cannabis research down under: Introducing the Lambert Initiative for Cannabinoid Therapeutics | Iain McGregor, PhD University of Sydney |
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| 10:00 am | Discussion/Future Directions | |
| 10:30 am | Break | |
| 11:00 am | Public health and safety implications of medicinal cannabis | |
| Moderator | Susan Tapert, PhD UC San Diego |
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| Cannabis & cognition: Budding evidence regarding the differential impact of recreational vs. medical use | Staci Gruber, PhD Harvard Medical School |
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| Cannabis and public safety: The challenge of cannabis-impaired driving | Thomas Marcotte, PhD UC San Diego |
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| Medicinal cannabis / legalization and the development of cannabis use problems | Alan Budney, PhD Dartmouth Geisel School of Medicine |
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| 11:50 am | Discussion/Future Directions | |
| 12:20 pm | Lunch & Poster-viewing | |
| 1:15 pm | Real-World Use | |
| Moderator | Kent Hutchison, PhD University of Colorado Boulder |
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| What's in real-world cannabis? | Ryan Vandrey, PhD Johns Hopkins University |
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| Cannabis based drug development activities at Ole Miss | Mahmoud ElSohly, PhD University of Mississippi |
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| Day to day in a cannabis clinic | Sherry Yafai, MD Santa Monica Emergency Medicine |
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| Industry Panel | Catherine Jacobson, PhD Tilray Tiffany Devitt Linda Honderd |
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| 2:25 pm | Discussion/Future Directions | |
| 2:55 pm | Policy, legal, and pragmatic issues in obtaining cannabis preparations for medical research | |
| Moderator | Igor Grant, MD UC San Diego |
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| Legalization experience | Lori Ajax California Bureau of Cannabis Control |
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| Update from NIDA: Current status and the future of research on marijuana and marijuana products | Steve Gust, PhD National Institute on Drug Abuse (NIDA) |
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| FDA and Cannabis: Our Regulatory Roles |
Dominic Chiapperino, PhD U.S. Food and Drug Administration |
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| Legal Challenges | Ellen Auriti, JD University of California, Office of the President |
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| 4:00 pm | Panel Discussion/Future Directions | |
| 4:30 pm | Open Discussion | |
| 5:00 pm | Adjourn | |
