Cannabis Use and the Endocannabinoid System in Bipolar Disorder

INVESTIGATORS: William Perry, Ph.D. & Jared Young, Ph.D.

STUDY LOCATION: University of California, San Diego

PROJECT TITLE: Cannabis Use and the Endocannabinoid System in Bipolar Disorder

PROJECT TYPE: Clinical Study

STATUS: PENDING

ABSTRACT:

Cannabis use is highly prevalent in people with Bipolar Disorder (BD) and likely results in significant cognitive and behavioral disturbance in a population already vulnerable to cognitive deficits. This study will look at the impact of chronic cannabis use as well as the effects of acute administration of the principal constituents of cannabis on cognition and brain levels of endogenous cannabinoids and the neurotransmitter dopamine. Parallel studies in rodent models of BD will enhance the understanding of the neurobiology of cannabis use from acute, chronic, and withdrawal perspectives, and may ultimately lead to novel treatment targets.

 

Igor Grant, MD

Introduction/Overview
CMCR Symposium, June 2018


Daniele Piomelli, MD, PhD, PharmD

The health impact of cannabis
CMCR Symposium, June 2018


Ziva Cooper, PhD

Therapeutic potential of cannabis for pain alone and as an adjunct to opioids
CMCR Symposium, June 2018


Iain McGregor, PhD

Medicinal cannabis research down under: Introducing the Lambert Initiative for Cannabinoid Therapeutics
CMCR Symposium, June 2018


Thomas Marcotte, PhD

Cannabis and public safety: The challenge of cannabis-impaired driving
CMCR Symposium, June 2018


Alan Budney, PhD

Medicinal cannabis / legalization and the development of cannabis use problems
CMCR Symposium, June 2018


Ryan Vandrey, PhD

What's in real-world cannabis?
CMCR Symposium, June 2018


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