The purpose of the Center for Medicinal Cannabis Research is to coordinate rigorous scientific studies to assess the safety and efficacy of cannabis and cannabis compounds for treating medical conditions.

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Some of the Parts: Is Marijuana’s “Entourage Effect” Scientifically Valid?

Angus Chen, Scientific American, April 20, 2017

If you believe budtender wisdom, consuming a strain called Bubba Kush should leave you ravenous and relaxed whereas dank Hippie Chicken should uplift you like a dreamy cup of coffee. But if you take pure, isolated delta-9-tetrahydrocannabinol, or THC—the main psychoactive ingredient in marijuana—you’ll experience “a high that has no specific character, so that seems boring,” says Mowgli Holmes, a geneticist and founder of a cannabis genetics company Phylos Bioscience.

What gives cannabis “character,” in Holmes’s view, are the hundreds of other chemicals it contains. These include THC’s cousin cannabinoids such as cannabidiol, along with other compounds called terpenes and flavonoids. Whereas terpenes are generally credited with giving pot its varied fragrances—limonene, for example, imparts a snappy, citrusy perfume—the cannabis industry and some researchers have espoused the controversial idea that such compounds can enhance or alter THC’s psychoactive and medicinal properties.

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When Retirement Comes With a Daily Dose of Cannabis

Winnie Hu, The New York Times, February 19, 2017

Ruth Brunn finally said yes to marijuana. She is 98.

She pops a green pill filled with cannabis oil into her mouth with a sip of vitamin water. Then Ms. Brunn, who has neuropathy, settles back in her wheelchair and waits for the jabbing pain in her shoulders, arms and hands to ebb.

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When Are You Too Stoned to Drive?

Beth Schwartzapfel, The Marshall Project, January 16, 2017

Late one February night in 2013, Massachusetts state trooper Eric French pulled over a blue SUV with its rear lights out. When he approached the car, he saw smoke and smelled pot. The driver, Thomas Gerhardt, could count backwards from 75 to 62 and recite the alphabet from D to Q. But he couldn’t stand on one leg or walk nine steps and turn, standard measures on a field sobriety test. The trooper determined that Gerhardt was impaired, and he was arrested and charged with driving under the influence of marijuana.

Was Gerhardt even high? And if he was, was he too high to drive safely?

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Igor Grant, MD

American Psychological Association Plenary Address: Marijuana as Medicine: Can we see past the smoke?
Denver, CO (August 2016)




Barth Wilsey, MD

Marijuana and Cannabinoids: A Neuroscience Research Summit;
Bethesda, MD (March 2016)



THE PSYCHIATRIC AND NEUROCOGNITIVE EFFECTS OF CANNABIS
(PDF)

Igor Grant, MD, FRCP(C) American Association for the Advancement of Science Annual Meeting

McGill University Health Centre - Research Institute
(February 2015)



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